tag:blogger.com,1999:blog-2467578050936938731.post4628933190747906963..comments2023-06-26T03:09:59.770-07:00Comments on Glutinous Thoughts: Persorption of Resistant Starch Granules: Should We Be Worried?Shmuel HaShualhttp://www.blogger.com/profile/00847767336618659705noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-2467578050936938731.post-87441927147491424722014-09-17T08:49:58.103-07:002014-09-17T08:49:58.103-07:00...Beta-glucans—usually acquired from mushrooms—ar......Beta-glucans—usually acquired from mushrooms—are are considered to be “keys” that turn on the body’s macrophage defense (immune) system. David Wolfe describes how they work, like this:<br /><br />------<br />David Wolfe said: “Specifically, here is how it works: the beta glucans found in [mushrooms], other herbs, foods, or supplements enter the body via the small intestine and are captured by the macrophages. To be activated by beta glucans, the macrophages must first “ingest” the beta glucans through specific beta glucan receptor sites on these cells’ membranes. Then the macrophages internalize and fragment the beta glucans within themselves and transport these fragments to the bone marrow (helping stimulate more stem cells) and to the reticuloendothelial system (RES). The beta glucans fragments are eventually released by the macrophages and taken up by other immune cells, including neutrophils , monocytes, natural killer cells, and dendritic cells, leading to numerous enhanced immune responses, 19 including adaptability against and deactivation of foreign pathogens, genotoxicity (toxins harmful to genetics), cancerous growth formations, and environmental toxicity.<br /><br />According to a study that appeared in the Journal of Hematology and Oconology in 2009, “animals pretreated with purified glucan particles are subsequently more resistant to bacterial, viral, fungal, and protozoan challenge, reject antigenically incompatible grafts more rapidly and produce higher titers of serum antibodies to specific antigens.”<br /><br />SOURCE: Wolfe, David (2012-09-11).<br />------<br /><br />When you put it all together, you can sort of see the big picture of what the body does with persorption. It selectively persorbs particles, perhaps based on their size, so that these particles can get exposed to the entire body and the immune system in a matter of minutes. And then the unneeded particles disappear — often filtered out by the liver or lymphatic system.<br /><br />I suspect as long as you are eating quantities of particles that are within the range of normal human consumption, you are fine. The amount of RS that most people consume supplementally (5g to 40g) is within the normal limits that would have been eaten by Andean indians or even Asians consuming Dioscorea opposita (a tuber high in resistant starch granules). I don’t see how that could be especially problematic within the context of the naturally occurring persorption that we have always been exposed to.<br /><br />The concern with persorption, if there is one, is likely from man made particles that the body may not be prepared to filter.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-2467578050936938731.post-9050569551480176672014-09-17T08:48:58.064-07:002014-09-17T08:48:58.064-07:00I researched this awhile back and thought I would ...I researched this awhile back and thought I would share my notes, in case this actually were to concern anybody…<br /><br />Volkheimer used 200g of potato starch to cause embolisms in his subjects. Think about that for a moment. That’s an enormous dose of starch granules. Even people who eat raw potato starch—for the resistant starch—rarely consume more than 40-50g per day. And it would be a challenge to eat more than 8-12g of starch granules in a day from food.<br /><br />Volkheimer believed that persorption was some kind of flaw in the gut that allowed starch granules to leak through. And if starch granules that were larger than a red blood cell (6-8 microns in diameter) could get stuck in the blood vessels and cause blockages and embolisms. This was theorized because some blood vessels are so tiny that the red blood cells must travel single-file to pass through. However, it’s highly unlikely that the lymph and blood vessels are not prepared to handle such intrusions. If not, I doubt our species would have been able to tolerate Underground Storage Organs (USOs). Furthermore, it’s well recognized that the liver is specifically designed to filter such particles from the blood.<br /><br />If we are going to worry about starch granules—which are often larger than the diameter of a red blood cell—then we must also worry about anything else that fits this criteria:<br /><br />Activated charcoal, has a particle size range of 1-150 microns, and seems to have the ability to detoxify the blood. These are surely persorbed as Volkheimer specifically mentions “charcoal” being persorbed in his subjects.<br /><br />As pointed out, above, carrots have a starch granule size of 4-26 microns, and should therefore cause embolisms according to Volkheimer.<br /><br />Raw unfiltered honey, contains pollen that range from 2.5 to 1,000 microns! Most honey producers will filter the pollen out their honey with sieves that range from 50 microns (heavily filtered) to 600 microns (lightly filtered). But, as we know, Hunter Gatherer populations tend to eat a lot of honey and they didn’t filter their honey with modern sieves. So, I can imagine lots of large and small pollen getting persorbed by Hunter Gatherers every day.<br /><br />It would seem that persorption probably isn’t some kind of design flaw in our bodies. Combine that with the practice of geophagy (eating dirts and clays) and you get the picture that these particles are probably supposed to temporarily roam through our blood vessels. Persorption appears to be an intentional mechanism with a purpose.<br /><br />Obligate carnivores consume raw meat, which is rich in glycans (glycolipids, glycoproteins, etc.), which is what we know of as animal fiber. Animal fiber is persorbed as well, and likely has a very wide range. Some of these glycans are probably used throughout the body. In fact, any fiber particle that is eaten from any food will surely become persorbed in the same manner.<br /><br />Glycosaminoglycans (GAGs) from blueberries literally get <a href="http://www.ncbi.nlm.nih.gov/pubmed/21925856" rel="nofollow">transported to your blood vessels and play a role in maintaining their health</a>. Without persorption, there would be no way for GAGs to contribute to the health of blood vessels....Anonymousnoreply@blogger.com